CCR7 Antikörper

Produktnummer ABIN7539624

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CCR7 in FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CCR7 Antikörper (ABIN7539624)

Target: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CCR7 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: G043H7

Produktdetails anti-CCR7 Antikörper

Verwendungszweck: AF/LE Purified Anti-Human CD197 Antibody [G043H7]

Spezifität: Human

Aufreinigung: Protein A/G Purified

Endotoxin-Niveau: Low Endotoxin: < 1.0 EU per mg of the antibody as determined by the LAL method.

Immunogen: Recombinant Human CD197 protein

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: FCM:2 μg/mL(1x10^5-5x10^5 cells)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: ≥ 1 mg/mL

Buffer: Sterile PBS.

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Details zu CCR7

Target: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Andere Bezeichnung: CD197

Hintergrund: The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants.

Gen-ID: 1236

UniProt: P32248

Pathways: Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process