Reaktivität: Mpox Virus
ELISA
Wirt: Human
Monoclonal
P2E5
Fc Tag
single-domain Antibody (sdAb)
Recombinant Antibody
Applikationshinweise
ELISA (recommended work dilution = 1:32,000)
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Product is supplied as a powder obtained from lyophilization of purified antibody in glycine solution. Reconstitute the antibody with sterile water to a final concentration of 1 mg/ml.
Konzentration
Lot specific
Lagerung
-20 °C
Informationen zur Lagerung
The antibody is stable for at least 1 year from the date of receipt when stored at -20°C to -70°C. Reconstituted antibody can also be aliquotted and stored at 4 °C for 1 month or at -20 °C to -70 °C in a manual defrost freezer for many months without detectable loss activity. Please avoid freeze-thaw cycles.
Haltbarkeit
12 months
Target
MPXV A29L
Hintergrund
Monkeypox is a rare zoonosis caused by monkeypox virus, which has become the most serious orthpoxvirus and consists of complex double stranded D. The cases are mostly in central and western Africa. The pathogenesis of monkeypox is that the virus invades the body from respiratory mucosa, multiplies in lymphocytes, and incurs into blood producing transient venereal toxemia. After the virus multiplies in cells, the cells can invade the blood and propagate to the skin of the whole body, causing lesions. A29L binds to cell surface heparin to promote fusion of viral membrane with host plasma membrane.