GLMN Antikörper (AA 151-250) (FITC)

Produktnummer ABIN721952

Der Kaninchen Polyklonal Anti-GLMN-Antikörper wurde für WB, FACS, IF (cc) und IF (p) validiert. Er ist geeignet, GLMN in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für GLMN Antikörper (AA 151-250) (FITC) (ABIN721952)

Target: GLMN (Glomulin, FKBP Associated Protein (GLMN))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLMN Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-GLMN Antikörper (FITC)

Bindungsspezifität: AA 151-250

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FK506 binding protein associated protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-GLMN Antikörper (FITC) (ABIN721952)

Huang, Xu, Cao, Cao, Zhang: "The expression of FOXJ1 in neurogenesis after transient focal cerebral ischemia." in: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, Vol. 40, Issue 3, pp. 403-9, (2013) (PubMed).

Details zu GLMN

Target: GLMN (Glomulin, FKBP Associated Protein (GLMN))

Andere Bezeichnung: FK506 binding protein associated protein

Hintergrund:

Synonyms: FAP, GVM, GLML, FAP48, FAP68, FKBPAP, VMGLOM, Glomulin, FK506-binding protein-associated protein, FKBP-associated protein, GLMN, GLMN_HUMAN

Background: Isoform 1: Regulatory component of cullin-RING-based SCF (SKP1-Cullin-F-box protein) E3 ubiquitin-protein ligase complexes.). Inhibits E3 ubiquitin ligase activity by binding to RBX1 (via RING domain) and inhibiting its interaction with the E2 ubiquitin-conjugating enzyme CDC34. Inhibits RBX1-mediated neddylation of CUL1. Required for normal stability and normal cellular levels of key components of SCF ubiquitin ligase complexes, including FBXW7, RBX1, CUL1, CUL2, CUL3, CUL4A, and thereby contributes to the regulation of CCNE1 and MYC levels (By similarity). Essential for normal development of the vasculature. Contributes to the regulation of RPS6KB1 phosphorylation

Gen-ID: 11146

UniProt: Q92990

Pathways: Tube Formation