KLRG1 Antikörper

Produktnummer ABIN7536931

Dieses Anti-KLRG1-Antikörper ist ein Golden Syrian Hamster Monoklonal-Antikörper zur Detektion von KLRG1 in FACS. Geeignet für Human.

Kurzübersicht für KLRG1 Antikörper (ABIN7536931)

Target: KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))

Reaktivität: Human

Wirt: Golden Syrian Hamster

Klonalität: Monoklonal

Konjugat: Dieser KLRG1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: 2F1

Produktdetails anti-KLRG1 Antikörper

Verwendungszweck: Purified Anti-Human/Mouse KLRG-1 Antibody [2F1]

Aufreinigung: Purified

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 μg per 10^6 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer.

Lagerung: 4 °C

Informationen zur Lagerung: This product can be stored at 2-8°C for 12 months. Do not freeze.

Haltbarkeit: 12 months

Details zu KLRG1

Target: KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))

Andere Bezeichnung: KLRG-1

Hintergrund: KLRG-1,MAFA, 2F1-Ag,Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag).? KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3.? It is composed of a homodimer of glycosylated 30-38 kD subunits.? Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells.? KLRG1 is also expressed on subsets of CD8+?and CD4+?cells, including CD4+?and CD8+?effector/memory cells, potent regulatory CD4+?T cells.? KLRG1 may be involved in regulating NK cell homeostasis.? KLRG2 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.

Gen-ID: 10219, 50928

UniProt: Q96E93, O88713