Interleukin 17a Antikörper

Produktnummer ABIN7536930

Der Maus Monoklonal Anti-Interleukin 17a-Antikörper wurde für ICFC validiert. Er ist geeignet, Interleukin 17a in Proben von Maus zu detektieren.

Kurzübersicht für Interleukin 17a Antikörper (ABIN7536930)

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Interleukin 17a Antikörper ist unkonjugiert

Applikation: Intracellular Flow Cytometry (ICFC)

Klon: 17F3

Produktdetails anti-Interleukin 17a Antikörper

Verwendungszweck: Purified Anti-Mouse IL-17A Antibody [17F3]

Aufreinigung: Purified

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 μg per 10^6 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Kommentare:

Matching Isotype Control: (ABIN7469768)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer.

Lagerung: 4 °C

Informationen zur Lagerung: This product can be stored at 2-8°C for 12 months. Do not freeze.

Haltbarkeit: 12 months

Details zu Interleukin 17a

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Andere Bezeichnung: IL-17A

Hintergrund: IL-17A,Interleukin-17A,Il17a,Ctla9,The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-18A?in vivo.

Gen-ID: 16171

UniProt: Q62386