MUC1 Antikörper
Kurzübersicht für MUC1 Antikörper (ABIN7529097)
Target
Alle MUC1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Verwendungszweck
- MUC1 Unconjugated Antibody
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Produktmerkmale
- The clone C-F2A, a mouse monoclonal antibody selectively binds to 500-1000 kD heterodimer transmembrane protein of the mucin family encoded in humans by the MUC1 gene known as MUC1 which also called as CD227. MUC1 is variably expressed on the surfaces of normal and malignant glandular and ductal epithelial cells, some hematopoietic cell lineages including subsets of T cells, B cells, monocytes, and dendritic cells. Due to its overexpression and aberrantly glycosylated in adenocarcinomas and in hematological malignancies, MUC1 (CD227) has been a target for tumor immunotherapeutic studies in mice and in humans.
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Aufreinigung
- Purified
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Reinheit
- >95 %
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Immunogen
- Human Milk Fat Globule Membranes
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Isotyp
- IgG2b, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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- MUC1 (Mucin 1 (MUC1))
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Andere Bezeichnung
- MUC1
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Gen-ID
- 4311
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NCBI Accession
- NC_00003
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UniProt
- P08473
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Pathways
- Negative Regulation of intrinsic apoptotic Signaling
Target
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