CD28 Antikörper (APC-Cy7)
Kurzübersicht für CD28 Antikörper (APC-Cy7) (ABIN7529062)
Target
Alle CD28 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Verwendungszweck
- CD28 APC-Cyanine7 Antibody
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Produktmerkmale
- The clone 28.2, a mouse monoclonal antibody selectively recognizes a 44 kDa type I cell surface glycoprotein known as CD28. It is expressed by all T cells and acts as a co-stimulatory receptor in support of the T cell receptor (TCR). CD28 exists as a homodimer with specificity for two known ligands, B7-1 (CD80) and B7-2 (CD86), which are primarily expressed by the activated B cells as well as other antigen-presenting cells. CD28-CD28 ligands signaling induces TCR functional activation resulting T cell proliferation, production of higher levels of IL-2 and enhancing T cell cytotoxicity.
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Aufreinigung
- Purified
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Reinheit
- >95 %
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Immunogen
- Murine T cells overexpressing human CD28 cDNA
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Isotyp
- IgG1, kappa
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anti-CD28 (CD28) (AA 1-120) antibody
CD28 Reaktivität: Human, Maus, Ratte FACS, WB, ELISA, IHC (fro), IF (p), IHC (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated
anti-CD28 (CD28) antibodyCD28 Reaktivität: Human, Non-Human Primate FACS, WB, IP, IHC (fro), ICC Wirt: Maus Monoclonal CD28-2 unconjugated
anti-CD28 (CD28) antibody (FITC)CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 FITC
anti-CD28 (CD28) antibodyCD28 Reaktivität: Human, Non-Human Primate FACS, WB, IP, Func, IHC (fro), ICC Wirt: Maus Monoclonal CD28-2 unconjugated
anti-CD28 (CD28) (AA 19-152) antibodyCD28 Reaktivität: Human FACS, ELISA Wirt: Kaninchen Monoclonal DM61 unconjugated Recombinant Antibody
anti-CD28 (CD28) antibodyCD28 Reaktivität: Ratte FACS, IP Wirt: Maus Monoclonal JJ319 unconjugated
anti-CD28 (CD28) antibody (PE)CD28 Reaktivität: Ratte FACS Wirt: Maus Monoclonal JJ319 PE
anti-CD28 (CD28) antibody (PE)CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 PE
anti-CD28 (CD28) antibody (APC)CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 APC
anti-CD28 (CD28) antibody (PerCP)CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 PerCP
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- 2-8°C, Conjugated antibodies should never be frozen.
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- CD28
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Andere Bezeichnung
- CD28
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Gen-ID
- 940
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UniProt
- P10747
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Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Target
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