MUM1 Antikörper (AA 401-500)

Produktnummer ABIN721195

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MUM1 in WB, IF (cc), IF (p), IHC (fro) und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.Es wurde in 1 Publikation zitiert.

Kurzübersicht für MUM1 Antikörper (AA 401-500) (ABIN721195)

Target: MUM1 (Melanoma Associated Antigen (Mutated) 1 (MUM1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MUM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-MUM1 Antikörper

Bindungsspezifität: AA 401-500

Verwendungszweck: MUM1 Polyclonal Antibody

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Sheep,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MUM1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:500-1000),

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-MUM1 Antikörper (ABIN721195)

Perez-Chacon, Adrados, Vallejo-Cremades, Lefebvre, Reed, Zapata: "Dysregulated TRAF3 and BCL2 Expression Promotes Multiple Classes of Mature Non-hodgkin B Cell Lymphoma in Mice." in: Frontiers in immunology, Vol. 9, pp. 3114, (2018) (PubMed).

Details zu MUM1

Target: MUM1 (Melanoma Associated Antigen (Mutated) 1 (MUM1))

Andere Bezeichnung: MUM1

Hintergrund:

Synonyms: EXPAND1, FLJ14868, FLJ22283, HSPC211, Melanoma associated antigen mutated 1, Melanoma ubiquitous mutated protein, MGC131891, MGC163315, MUM 1, MUM-1, MUM1, MUM1_HUMAN, Mutated melanoma associated antigen 1, Mutated melanoma-associated antigen 1, Protein expandere, PWWP domain containing protein MUM1, PWWP domain-containing protein MUM1.

Background: Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.

Gen-ID: 84939

Pathways: Chromatin Binding