The mouse monoclonal antibody TrMab-6 recognizes an extracellular epitope of TROP2, a type I transmembrane glycoprotein. This antibody is usefull for detection of TROP2 in breast cancer.
Flow cytometry: Recommended dilution: 1-4 μg/mL. Western blotting: Recommended dilution: 1 μg/mL. Immunocytochemistry: Recommended dilution: 10 μg/mL, the cells can be fixed with 4 % PFA and permeabilized with 0.1 % Triton X-100 before antibody staining, when needed. Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/mL. Heat-mediated antigen retrieval in citrate buffer, pH = 6.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
1 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
Store at 2-8°C. Do not freeze.
Target
TACSTD2
(Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))
Andere Bezeichnung
TROP2
Hintergrund
Tumor associated calcium signal transducer 2,TROP2 is a cell surface receptor that transduces calcium signals. It belongs to carcinoma-associated antigens. Mutations of TROP2 have been associated with gelatinous drop-like corneal dystrophy.,TACSTD2, EGP1, GP50, M1S1, GA733-1