TIAL1 Antikörper
Kurzübersicht für TIAL1 Antikörper (ABIN7506023)
Target
Alle TIAL1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-TIAR Purified
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Produktmerkmale
- The mouse monoclonal antibody 6E3 recognizes TIAR, an ubiquitously expressed approximately 42 kDa intracellular RNA-binding protein.
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Aufreinigung
- Purified by protein-A affinity chromatography.
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Immunogen
- GST-tagged recombinant human TIAR
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Isotyp
- IgG2a, kappa
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anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) (AA 266-375) antibody
TIAL1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) antibodyTIAL1 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) (AA 161-365) antibodyTIAL1 Reaktivität: Human, Maus, Ratte, Hund, Frosch WB, IHC, IP, IF Wirt: Maus Monoclonal 6-TIAR unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) (AA 1-252) antibodyTIAL1 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) (Internal Region) antibodyVerified TIAL1 Reaktivität: Human WB, ELISA, IHC Wirt: Ziege Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) (AA 1-90) antibodyTIAL1 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) (Internal Region) antibodyTIAL1 Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) (AA 9-277) antibodyTIAL1 Reaktivität: Human ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) (C-Term) antibodyTIAL1 Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd, Zebrafisch (Danio rerio), Huhn, Meerschweinchen, Fledermaus, Schwein, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) (AA 275-325) antibodyTIAL1 Reaktivität: Human, Maus IHC, IP, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Flow cytometry: Intracellular staining, recommended dilution: 5 μg/mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Do not freeze
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))
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Andere Bezeichnung
- TIAR
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Hintergrund
- TIA1 cytotoxic granule associated RNA binding prot,TIAR is an ubiquitously expressed RNA-binding protein, which regulates translational control, splicing, and other activities, including apoptosis. TIAR attenuates CDK1 activity, and is essential for the G2/M checkpoint. It accumulates in nuclear foci in late G2 phase and prophase in cells under replication stress. In steady state TIAR shuttles between the cytoplasm and the nucleus, probably as a part of nucleocytoplasmic transport of mRNA, but under stress conditions it accumulates mRNA molecules in granules and prevents their translation. Nucleolytic activity of TIAR against attacked target cells of cytotoxic lymphocytes has also been reported. Similarly, e.g. in permeabilized thymocytes TIAR triggers DNA fragmentation.,TCBP, TIAL1
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Gen-ID
- 7073
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UniProt
- Q01085
Target
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