SIGLEC10 Antikörper (Extracellular Domain)
Kurzübersicht für SIGLEC10 Antikörper (Extracellular Domain) (ABIN7506009)
Target
Alle SIGLEC10 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- Extracellular Domain
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Verwendungszweck
- Anti-Hu SIGLEC10 Purified
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Produktmerkmale
- The mouse monoclonal antibody 5G6 recognizes an extracellular epitope of human SIGLEC10, a sialic acid-binding lectin expressed on subsets of human leucocytes.
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Aufreinigung
- Purified by protein-A affinity chromatography.
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Immunogen
- SIGLEC10 extracellular domain fused with human IgG1 Fc fragment
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Isotyp
- IgG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Do not freeze
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))
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Andere Bezeichnung
- SIGLEC10
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Hintergrund
- Sialic acid binding Ig like lectin 10,SIGLEC10 is a CD33-related receptor of sialoglycans, expressed on eosinophils, monocytes, a subpopulation of NK cells, and at lower level on B cells. Its murine ortholog is Siglec G. SIGLEC10 seems to act as an immunomodulatory receptor, which binds to VAP-1, a glycoprotein expressed on endothelium under inflammatory conditions. Another ligand of SIGLEC10 is CD24, a marker of poorer prognosis in carcinomas.,PRO940, SGL2
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Gen-ID
- 89790
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UniProt
- Q96LC7
Target
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