Der Maus Monoklonal Anti-SIGLEC9-Antikörper wurde für WB, ELISA, FACS, ICC und IP validiert. Er ist geeignet, SIGLEC9 in Proben von Human zu detektieren.
The mouse monoclonal antibody K8 recognizes an extracellular epitope of CD239, a type I transmembrane glycoprotein expressed above all on monocytes, neutrophils, and a minor population of CD16+CD56- cells.
Sialic acid binding Ig like lectin 9,CD329 is a type I transmembrane glycoprotein of siglec family, which contains intracellular ITIM motif, and a SLAM-like motif, that acts as a docking site for SAP. CD329 can regulate TCR signaling by recruitment of SHP-1, which results in down-regulation of TCR-based gene transcription. It is expressed above all on monocytes, neutrophils, and a minor population of CD16+CD56- cells, weaker expression is detectable in some B cells, NK cells, and T cells.,SIGLEC9