FCRL3 Antikörper (PE)

Produktnummer ABIN7505905

Der Maus Monoklonal Anti-FCRL3-Antikörper wurde für FACS validiert. Er ist geeignet, FCRL3 in Proben von Human zu detektieren.

Kurzübersicht für FCRL3 Antikörper (PE) (ABIN7505905)

Target: FCRL3 (Fc Receptor-Like 3 (FCRL3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FCRL3 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: H5

Produktdetails anti-FCRL3 Antikörper (PE)

Verwendungszweck: Anti-Hu CD307c PE

Spezifität: The mouse monoclonal antibody H5 recognizes an epitope within extracellular part of CD307c, a transmembrane glycoprotein expressed mainly on NK cells, and T and B cell subsets.

Aufreinigung: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: DNA-immunization followed by a boost with CD307c transfected cells

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Details zu FCRL3

Target: FCRL3 (Fc Receptor-Like 3 (FCRL3))

Andere Bezeichnung: CD307c

Hintergrund: Fc receptor like 3,CD307c is a type I transmembrane glycoprotein of the Fc receptor family. It contains both ITAM and ITIM motifs in its cytoplasmic domain. CD307c is expressed on the surface of NK cells, and T, Treg, B and plasma cell subsets. It seems to play a role in the regulation of immune response. Defects in CD307c function can result in autoimmune diseases, e.g. rheumatoid arthritis or systemic lupus erythematosus.,FcRL3, IRTA3

Gen-ID: 115352

UniProt: Q96P31