CD245 Antikörper
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- Target
- CD245
- Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Unkonjugiert
- Applikation
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)
- Verwendungszweck
- Anti-Hu CD245 Purified
- Spezifität
- The mouse monoclonal antibody DY12 recognizes an extracellular epitope of CD245, a transmembrane protein expressed mainly by peripheral blood lymphocytes, NK cells, monocytes, granulocytes and platelets.
- Aufreinigung
- Purified by protein-A affinity chromatography.
- Immunogen
- human NK-type YT2C2 cells
- Klon
- DY12
- Isotyp
- IgG1 kappa
-
-
- Applikationshinweise
- Flow cytometry: Recommended dilution: 1-5 μg/mL.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
-
- Target
- CD245
- Hintergrund
- CD245 is a 220-250 kDa transmembrane protein of unknown structure. It is expressed at lower level on resting blood lymphocytes, granulocytes, platelets, and thymocytes, and at high level on monocytes and on IL-2-dependent T cell lines. It is also expressed on Ewing sarcoma and osteosarcoma cell lines. CD245 seems to act as a costimulation molecule of T and NK cells.,p220/240, DY12, DY35
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