CD207 Antikörper

Produktnummer ABIN7505884

Der Maus Monoklonal Anti-CD207-Antikörper wurde für ELISA, FACS, ICC und IHC (fro) validiert. Er ist geeignet, CD207 in Proben von Human und Non-Human Primate zu detektieren.

Kurzübersicht für CD207 Antikörper (ABIN7505884)

Target: CD207 (CD207 Molecule, Langerin (CD207))

Reaktivität: Human, Non-Human Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD207 Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 2G3

Produktdetails anti-CD207 Antikörper

Verwendungszweck: Anti-Hu CD207 Purified

Spezifität: The mouse monoclonal antibody 2G3 recognizes an extracellular/luminal epitope of CD207, a transmembrane protein selectively expressed by Langerhans cells and by some other dendritic cell subsets. This antibody clone can target vaccine-peptides to dendritic cells.

Aufreinigung: Purified by protein-A affinity chromatography.

Immunogen: Fusion protein of human CD207 extracellular part and IgG Fc fragment

Isotyp: IgG1 lambda

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 0.5-4 μg/mL. Extracellular and intracellular staining.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu CD207

Target: CD207 (CD207 Molecule, Langerin (CD207))

Andere Bezeichnung: CD207

Hintergrund: CD207 Molecule,CD207 is a 40 kDa type II transmembrane glycoprotein of the C-type lectin family. It binds to mannose-bearing glycoproteins and glycolipids of microbial and viral antigens, including HIV gp120. CD207 is expressed only in Langerhans cells, which are immature dendritic cells of the epidermis and mucosa, and its expression decreases during Langerhans cells maturation. Upon antigen binding CD207 localizes to the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed membranes, which leads to a nonclassical antigen-processing pathway.,CLEC4K, langerin

Gen-ID: 50489

UniProt: Q9UJ71