Thrombomodulin Antikörper

Produktnummer ABIN7505855

Dieses Anti-Thrombomodulin-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Thrombomodulin in FACS. Geeignet für Human.

Kurzübersicht für Thrombomodulin Antikörper (ABIN7505855)

Target: Thrombomodulin (THBD)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Thrombomodulin Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: M80

Produktdetails anti-Thrombomodulin Antikörper

Verwendungszweck: Anti-Hu CD141 Purified

Spezifität: The mouse monoclonal antibody M80 recognizes an extracellular epitope of CD141, a 75 kDa transmembrane glycoprotein expressed mainly on macrophages, monocytes, platelets and endothelial cells.

Aufreinigung: Purified by protein-A affinity chromatography.

Immunogen: MV4-11 cell line

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1-5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu Thrombomodulin

Target: Thrombomodulin (THBD)

Andere Bezeichnung: CD141

Hintergrund: Thrombomodulin,CD141, also known as thrombomodulin or fetomodulin, is a single chain type I transmembrane glycoprotein serving as a receptor for thrombin and as an important cofactor in the protein C anticoagulant system, but it is also involved in embryonic and atherosclerotic plaque development. CD141 is expressed mainly on macrophages, monocytes, a subpopulation of myeloid dendritic cells, on platelets and endothelial cells, but also e.g. on keratinocytes (epithelium). After binding to thrombin, CD141 activates protein C, which degrades clotting factors Va and VIIIa, and as a consequence the amount of thrombin is reduced. Mutations in the CD141 gene can cause a thromboembolic disease known as inherited thrombophilia.,Thrombomodulin, fetomodulin, THBD, THRM, THPH12, TM

Gen-ID: 7056

UniProt: P07204