Kurzübersicht für Blood Group ABH Antikörper (PE) (ABIN7505845)
Target
Blood Group ABH
Reaktivität
Human
Wirt
Maus
Klonalität
Monoklonal
Konjugat
Dieser Blood Group ABH Antikörper ist konjugiert mit PE
Applikation
Flow Cytometry (FACS)
Klon
HE-10
Verwendungszweck
Anti-Blood Group ABH PE
Spezifität
The mouse monoclonal antibody HE-10 agglutinates erythrocytes of group A, and is excellent as a tumour marker in patients of blood group B and 0. It does not agglutinate erythrocytes of group B and 0. Study with specific oligosaccharides showed that the antibody HE-10 reacts with A and H antigens with chain types 3 and 4 and it does not react with A disaccharide, A trisaccharide, A type 1, A type 2, ALeb. The antibody HE-10 does not react with normal tissue sections of donors with blood group B and 0 but it reacts specifically with malignant tissues.
Aufreinigung
Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Immunogen
Mixture of erythrocytes of group A1 and glycoprotein fraction isolated from saliva of secretors with blood group A.