Integrin beta 3 Antikörper (PE)
Kurzübersicht für Integrin beta 3 Antikörper (PE) (ABIN7489343)
Target
Alle Integrin beta 3 (ITGB3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Verwendungszweck
- CD61 PE Antibody
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Produktmerkmale
- The clone C-61.13, a mouse monoclonal antibody, specifically binds to the 90-110 kDa integral cell-surface protein known as CD61 or Integrin beta-3 (β3) that in humans is encoded by the ITGB3 gene. CD61 is expressed on the surface of platelets and megakaryocytes. CD61 (platelet glycoproteins IIIa) and CD41 (platelet glycoprotein IIb) form a calcium-dependent heterodimeric complex. This glycoprotein complex (GPIIb-IIIa) binds plasma proteins, such as fibrinogen, fibronectin, von Willebrand factor, and vitronectin, and plays a critical role in platelet aggregation.
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Aufreinigung
- Purified
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Reinheit
- >95 %
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Immunogen
- Recombinant human ITGB3 protein
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- 2-8°C, Conjugated antibodies should never be frozen.
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- Integrin beta 3 (ITGB3)
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Andere Bezeichnung
- CD61
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Gen-ID
- 933
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NCBI Accession
- NM_001771
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UniProt
- P20273
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
Target
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