CD28 Antikörper (FITC)

Produktnummer ABIN7489277

Der Maus Monoklonal Anti-CD28-Antikörper wurde für FACS validiert. Er ist geeignet, CD28 in Proben von Human zu detektieren.

Kurzübersicht für CD28 Antikörper (FITC) (ABIN7489277)

Target: CD28

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD28 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Güteklasse: GMP Grade

Klon: 28-2

Produktdetails anti-CD28 Antikörper (FITC)

Verwendungszweck: CD28 FITC Antibody

Produktmerkmale: The clone 28.2, a mouse monoclonal antibody selectively recognizes a 44 kDa type I cell surface glycoprotein known as CD28. It is expressed by all T cells and acts as a co-stimulatory receptor in support of the T cell receptor (TCR). CD28 exists as a homodimer with specificity for two known ligands, B7-1 (CD80) and B7-2 (CD86), which are primarily expressed by the activated B cells as well as other antigen-presenting cells. CD28-CD28 ligands signaling induces TCR functional activation resulting T cell proliferation, production of higher levels of IL-2 and enhancing T cell cytotoxicity.

Aufreinigung: Purified

Reinheit: >95 %

Immunogen: Murine T cells overexpressing human CD28 cDNA

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: We recommend that every lab carries out an initial titration study before running your samples to ensure that the optimal concentration is selected for your application.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C, Conjugated antibodies should never be frozen.

Details zu CD28

Target: CD28

Andere Bezeichnung: CD28

Gen-ID: 940

UniProt: P10747

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response