Rekombinanter Hemagglutinin Antikörper
Kurzübersicht für Rekombinanter Hemagglutinin Antikörper (ABIN7487730)
Target
Alle Hemagglutinin (HA) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Verwendungszweck
- Anti-HA [CR6261], Human IgG1, kappa
-
Spezifität
- This antibody binds hemaglutinin of most group 1 influenza viruses. CR6261 recognizes a highly conserved helical region in the membrane-proximal stem of HA1/HA2.
-
Produktmerkmale
-
Original Species of Ab: Human
Original Format of Ab: IgG1
-
Aufreinigung
- Protein A affinity purified
-
Immunogen
- The original antibody was isolated using phage display from the IgM+ memory B cells of a healthy individual vaccinated against influenza.
-
Isotyp
- IgG1 kappa
-
-
anti-Hemagglutinin antibody (Influenza A Virus) (AA 128-143)
HA Reaktivität: Influenza A Virus WB, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Hemagglutinin antibody (Influenza A Virus H9N2) (AA 9-28)HA Reaktivität: Influenza A Virus H9N2 WB, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Hemagglutinin antibody (Influenza A Virus H1N1 (A/California/04/2009)) (AA 151-250)HA Reaktivität: Influenza A Virus H1N1, Virus ELISA, WB, IF (p), IF (cc), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Hemagglutinin antibody (Influenza A Virus) (AA 72-88)HA Reaktivität: Influenza A Virus WB Wirt: Kaninchen Polyclonal unconjugated
anti-Hemagglutinin antibody (Influenza A Virus H1N1 (A/Swine/Iowa/15/1930 H1N1)) (AA 205-220)HA Reaktivität: Influenza A Virus H1N1 WB Wirt: Kaninchen Polyclonal unconjugated
anti-Hemagglutinin antibody (Influenza A Virus H9N2) (AA 212-225)HA Reaktivität: Influenza A Virus H9N2 WB Wirt: Kaninchen Polyclonal unconjugated
anti-Hemagglutinin antibody (Influenza A Virus) (AA 17-338)HA Reaktivität: Influenza A Virus WB Wirt: Maus Monoclonal 4E10C10 unconjugated
-
-
Applikationshinweise
- The antibody neutralizes the virus by blocking conformational rearrangements associated with membrane fusion. CR6261 neutralizes multiple influenza subtypes, including H1, H2, H5, H6, H8, and H9, and protects mice from lethal challenge with H1N1 and H5N1 viruses when administered up to five days post-infection (PMID: 19251591). It is reported that Oseltamivir/Zanamivir may congruously improve the therapeutic efficacy of CR6261 (PMID: 22693576).
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1 mg/mL
-
Buffer
- PBS with 0.02 % Proclin 300.
-
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
-
-
- Hemagglutinin (HA)
-
Andere Bezeichnung
- Hemagglutinin
-
Substanzklasse
- Influenza Protein
-
Hintergrund
- Hemagglutinin, Avian Influenza Virus, AIV, H1N1, H5N1, Influenza A virus
-
UniProt
- Q9WFX3
Target
-
