Rekombinanter CRP Antikörper

Produktnummer ABIN7487718

Der Kaninchen Chimeric Anti-CRP-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, CRP in Proben von Human zu detektieren.

Kurzübersicht für Rekombinanter CRP Antikörper (ABIN7487718)

Target: CRP (C-Reactive Protein (CRP))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser CRP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: P03

Produktdetails anti-CRP Antikörper

Verwendungszweck: Anti-CRP [P03], Rabbit IgG, kappa

Spezifität: This antibody reacts with human C reactive protein, which is a pentameric protein found in blood plasma. It is an acute phase reactive protein of hepatic origin. It is an important defense molecule for the body and its plasma concentration increases sharply during tissue damage, inflammation and bacterial infection. It promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. It can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Aufreinigung: Protein A affinity purified

Immunogen: The original antibody was generated by immunizing BALB/c mice with C-reactive protein extracted from human plasma.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: Indirect ELISA was used for the primary screening of the hybridomas showing selective binding for human CRP. Spicy Root peroxidase labeled scFv P03 was used for the identification of natural CRP extracted from denatured and non-denatured blood in a western blot assay. This antibody in combination with P24 was also used in the double antibody sandwich detection of natural human CRP. The combination of P03 and P24 antibody was also used for the generation of time-resolved fluorescence immunoassay card for detection of C-reactive protein (CN105842440).

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu CRP

Target: CRP (C-Reactive Protein (CRP))

Andere Bezeichnung: CRP

Hintergrund: C reactive protein, PTX1, C-reactive protein

UniProt: P02741

Pathways: Carbohydrate Homeostasis