Rekombinanter CD8 Antikörper
Kurzübersicht für Rekombinanter CD8 Antikörper (ABIN7487708)
Target
Alle CD8 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-CD8 [G10-1], Rabbit IgG, kappa
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Spezifität
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This antibody is specific for human CD8, and binds human CD8+ T cells. It also cross-reacts with non-human primate CD8, including that of Macaca nemestrina (Southern pig-tailed macaque).
Application Notes original Clone: This antibody has been used to stain cells expressing CD8 by indirect immunofluorescence (Uckun et al, 1989) and in immunohistochemical analysis of aortic and iliac artery tissue from nonhuman primates (Masuda & Ross, 1989). It has also been employed in immunoprecipitation and gel electrophoresis experiments to investigate cell surface CD8 complexes (Ledbetter et al, 1985). A FITC-conjugated version of this antibody has been used to identify T cell populations in flow cytometry experiments (Chen et al, 2003). When conjugated to the ribosome-inhibitory protein ricin, this antibody acts as a potent CD8+ T cell-directed immunotoxin (Uckun et al, 1989).
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Kreuzreaktivität
- Macaca nemestrina
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Produktmerkmale
- This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
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Aufreinigung
- Protein A affinity purified
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Immunogen
- Human CD8.
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Isotyp
- IgG, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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OriginalSpeciesName: Mouse
OriginalFormat: IgG2a
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CD8
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Andere Bezeichnung
- CD8
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Hintergrund
- Cluster of differentiation 8, G10.1, Tp32
Target
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