PLA2G6 Antikörper (AA 651-750)

Produktnummer ABIN720281

Produktdetails anti-PLA2G6 Antikörper

Target: PLA2G6 (Phospholipase A2, Group VI (Cytosolic, Calcium-Independent) (PLA2G6))

Bindungsspezifität: AA 651-750

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLA2G6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CaI-PLA2/PLA2G6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu PLA2G6

Target: PLA2G6 (Phospholipase A2, Group VI (Cytosolic, Calcium-Independent) (PLA2G6))

Andere Bezeichnung: CaI-PLA2 (PLA2G6 Produkte)

Synonyme: zgc:77476 antikoerper, wu:fc06g09 antikoerper, PNPLA9 antikoerper, MGC83523 antikoerper, PLA2G6 antikoerper, BB112799 antikoerper, iPLA(2)beta antikoerper, iPLA2 antikoerper, iPLA2beta antikoerper, CaI-PLA2 antikoerper, GVI antikoerper, INAD1 antikoerper, IPLA2-VIA antikoerper, NBIA2 antikoerper, NBIA2A antikoerper, NBIA2B antikoerper, PARK14 antikoerper, PLA2 antikoerper, iPla2 antikoerper, phospholipase A2, group VI (cytosolic, calcium-independent) antikoerper, phospholipase A2 group VI antikoerper, phospholipase A2 group VI S homeolog antikoerper, 85/88 kDa calcium-independent phospholipase A2 antikoerper, phospholipase A2, group VI antikoerper, pla2g6 antikoerper, PLA2G6 antikoerper, pla2g6.S antikoerper, LOC100445065 antikoerper, Pla2g6 antikoerper

Hintergrund:

Synonyms: GVI, PLA2, INAD1, NBIA2, iPLA2, NBIA2A, NBIA2B, PARK14, PNPLA9, CaI-PLA2, IPLA2-VIA, iPLA2beta, 85/88 kDa calcium-independent phospholipase A2, Group VI phospholipase A2, GVI PLA2, Intracellular membrane-associated calcium-independent phospholipase A2 beta, iPLA2-beta, Patatin-like phospholipase domain-containing protein 9, PLA2G6, PLPLA9

Background: Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F-actin polymerization at the pseudopods. Isoform ankyrin-iPLA2-1 and isoform ankyrin-iPLA2-2, which lack the catalytic domain, are probably involved in the negative regulation of iPLA2 activity.

Gen-ID: 8398

UniProt: O60733

Pathways: Positive Regulation of Peptide Hormone Secretion