Dieses Anti-Trastuzumab-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Trastuzumab in . Geeignet für Human.
Produktnummer ABIN7482306
Kurzübersicht für Rekombinanter Trastuzumab Antikörper (ABIN7482306)
Target
Trastuzumab
Antikörpertyp
Recombinant Antibody
Reaktivität
Human
Wirt
Maus
Klonalität
Monoklonal
Klon
AY1b
Verwendungszweck
Anti-Trastuzumab Antibody (AY1b) (recommended for PK/PD)
Produktmerkmale
Anti-idiotypic Antibodies
Immunogen
Anti-Trastuzumab Antibody (AY1b) are expressed from human 293 cells (HEK293).
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Lagerung
-20 °C
Target
Trastuzumab
Hintergrund
Trastuzumab, is a monoclonal antibody used to treat breast cancer. Specifically it is used for breast cancer that is HER2 receptor positive. Trastuzumab works by binding to the HER2 receptor and slowing down cell duplication. Trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein.