Kurzübersicht für Rekombinanter Bevacizumab Antikörper (ABIN7482170)
Target
Bevacizumab
Antikörpertyp
Recombinant Antibody
Reaktivität
Human
Wirt
Maus
Klonalität
Monoklonal
Konjugat
Dieser Bevacizumab Antikörper ist unkonjugiert
Güteklasse
MALS verified
Klon
AY10
Verwendungszweck
Anti-Bevacizumab Antibody (AY10) (MALS verified, recommended for PK/PD)
Produktmerkmale
Anti-idiotypic Antibodies
Immunogen
Mouse monoclonal antibody is produced from a hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with Bevacizumab F(ab')2.
Reaktivität: Human
Wirt: Maus
Monoclonal
AY13
Biotin
Recombinant Antibody
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Lagerung
-20 °C
Target
Bevacizumab
Substanzklasse
Antibody
Hintergrund
A recombinant humanized monoclonal IgG1 antibody that binds to and inhibits the biologic activity of human vascular endothelial growth factor (VEGF). Bevacizumab contains human framework regions and the complementarity-determining regions of a murine antibody that binds to VEGF. Bevacizumab is produced in a Chinese Hamster Ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin and has a molecular weight of approximately 149 kilodaltons.