Rekombinanter MUC1 Antikörper

Produktnummer ABIN7477525

Dieses Anti-MUC1-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von MUC1 in IHC. Geeignet für Human.

Kurzübersicht für Rekombinanter MUC1 Antikörper (ABIN7477525)

Target: MUC1 (Mucin 1 (MUC1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser MUC1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: MSVA-672R

Produktdetails anti-MUC1 Antikörper

Immunogen: Recombinant human MUC1 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:75-1:150

Kommentare:

Positive Control: Kidney: Distal tubuli and collecting ducts must show a strong cytoplasmic MUC1 staining while the staining should be at least moderate in the parietal and visceral sheets of the Bowman's capsule and largely absent in proximal tubuli.

Negative Control: Colon: MUC1 staining should be very weak or absent in colonic epithelium.

Protokoll: Manual Protocol: Freshly cut sections should be used (less than 10 days between cutting and staining). Heat-induced antigen retrieval for 5 minutes in an autoclave at 121 °C in pH 7,8 Target Retrieval Solution buffer. Apply the antibody at a dilution of 1:100 at 37 °C for 60 minutes. Visualization of bound antibody by the EnVision Kit (Dako, Agilent) according to the manufacturer's directions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non- hazardous.

Details zu MUC1

Target: MUC1 (Mucin 1 (MUC1))

Andere Bezeichnung: MUC1 / EMA

Hintergrund: Breast carcinoma-associated antigen DF3, CA15-3, Carcinoma- associated mucin Episialin, Epithelial Membrane Antigen (EMA), H23AG, KL-6, MAM6, MUC-1, MUC-1/SEC, MUC-1/X, MUC1- alpha, MUC1-beta, MUC1-CT, MUC1-NT, MUC1/ZD, Mucin 1 cell surface associated, Mucin-1 subunit beta, Peanut-reactive urinary mucin, PEM, PEMT, Polymorphic epithelial mucin, PUM, Tumor-associated epithelial membrane antigen,MUC1 / EMA antibody validated for immunohistochemistry on 76 different Normal Tissues

UniProt: P15941

Pathways: Negative Regulation of intrinsic apoptotic Signaling