MACC1 Antikörper (N-Term)

Produktnummer ABIN7469483

Dieses Anti-MACC1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MACC1 in WB. Geeignet für Human.

Kurzübersicht für MACC1 Antikörper (N-Term) (ABIN7469483)

Target: MACC1 (Metastasis Associated in Colon Cancer 1 (MACC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MACC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MACC1 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human MACC1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: A431

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.14 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu MACC1

Target: MACC1 (Metastasis Associated in Colon Cancer 1 (MACC1))

Andere Bezeichnung: MACC1

Hintergrund:

Synonyms: MET transcriptional regulator MACC1 , 7A5 , SH3BP4L

Background: MACC1 is a key regulator of the hepatocyte growth factor (HGF, MIM 142409)-HGF receptor (HGFR, or MET, MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM]

Molekulargewicht: 97 kDa

Gen-ID: 346389

UniProt: Q6ZN28