SLUG Antikörper

Produktnummer ABIN7468987

Der Kaninchen-Polyklonal Anti-SLUG-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet zum Nachweis von SLUG in Proben aus Human. }

Kurzübersicht für SLUG Antikörper (ABIN7468987)

Target: SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLUG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SLUG Antikörper

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human SLUG. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:10000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: human SLUG-transfected 293T cells , U87-MG , SK-N-SH , IMR32 , SK-N-AS , NT2D1 Validation: Orthogonal, Overexpression

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.18 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu SLUG

Target: SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))

Andere Bezeichnung: snail family transcriptional repressor 2

Hintergrund:

Synonyms: snail family transcriptional repressor 2 , SLUG , SLUGH , SLUGH1 , SNAIL2 , WS2D

Background: This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq]

Molekulargewicht: 30 kDa

Gen-ID: 6591

UniProt: O43623