TNNT1 Antikörper

Produktnummer ABIN7468979

Produktdetails anti-TNNT1 Antikörper

Target: TNNT1 (Slow Skeletal Troponin T (TNNT1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNNT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Schwein

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Full length human Troponin T1 (slow) skeletal muscle Recombinant protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: H1299

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.89 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu TNNT1

Target: TNNT1 (Slow Skeletal Troponin T (TNNT1))

Andere Bezeichnung: troponin T1, slow skeletal type (TNNT1 Produkte)

Synonyme: ANM antikoerper, NEM5 antikoerper, STNT antikoerper, TNT antikoerper, TNTS antikoerper, TNNI1 antikoerper, AW146156 antikoerper, Tnt antikoerper, sTnT antikoerper, ssTnT antikoerper, Fang2 antikoerper, tnTs antikoerper, Tnnt antikoerper, zgc:193831 antikoerper, zgc:193865 antikoerper, troponin T1, slow skeletal type antikoerper, troponin I1, slow skeletal type antikoerper, troponin T1, skeletal, slow antikoerper, troponin T1, slow skeletal type S homeolog antikoerper, troponin T type 1 (skeletal, slow) antikoerper, TNNT1 antikoerper, TNNI1 antikoerper, Tnnt1 antikoerper, tnnt1.S antikoerper, tnnt1 antikoerper

Hintergrund:

Synonyms: troponin T1, slow skeletal type , ANM , NEM5 , STNT , TNT , TNTS

Background: This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Molekulargewicht: 33 kDa

Gen-ID: 7138

UniProt: P13805