Protein/nucleic Acid Deglycase DJ-1 (PARK7) (N-Term) Antikörper

Produktnummer ABIN7468819

Der Kaninchen Polyklonal anti-Protein/nucleic Acid Deglycase DJ-1 Antikörper wird verwendet zum Nachweis von Protein/nucleic Acid Deglycase DJ-1 in Proben von Human. Er wurde validiert für WB und IHC (p).

Kurzübersicht für Protein/nucleic Acid Deglycase DJ-1 (PARK7) (N-Term) Antikörper (ABIN7468819)

Target: Protein/nucleic Acid Deglycase DJ-1 (PARK7)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: KO Validated

Produktdetails

Bindungsspezifität: N-Term

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Park7 / DJ-1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:20000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: 293T , A431 , HeLa , HepG2 , U87-MG , SK-N-SH , IMR32 , SK-N-AS Validation: KO/KD

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Antigendetails

Target: Protein/nucleic Acid Deglycase DJ-1 (PARK7)

Andere Bezeichnung: Parkinsonism associated deglycase

Hintergrund:

Synonyms: Parkinsonism associated deglycase , DJ-1 , DJ1 , GATD2 , HEL-S-67p

Background: The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]

Molekulargewicht: 20 kDa

Gen-ID: 11315

UniProt: Q99497