KAT2A Antikörper (C-Term)

Produktnummer ABIN7468506

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch KAT2A in WB, IF und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für KAT2A Antikörper (C-Term) (ABIN7468506)

Target: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KAT2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-KAT2A Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody was raised against KAT2A protein, and based on sequence homology, it may cross react with KAT2B protein.

Kreuzreaktivität: Human, Maus

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human GCN5. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: NIH-3T3 , JC , BCL-1 Validation: Orthogonal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu KAT2A

Target: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Andere Bezeichnung: lysine acetyltransferase 2A

Hintergrund:

Synonyms: lysine acetyltransferase 2A , GCN5 , GCN5L2 , PCAF-b , hGCN5

Background: KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM]

Molekulargewicht: 94 kDa

Gen-ID: 2648

UniProt: Q92830

Pathways: Chromatin Binding, Tube Formation