ABCB7 Antikörper

Produktnummer ABIN7468006

Der Kaninchen Polyklonal Anti-ABCB7-Antikörper wurde für WB validiert. Er ist geeignet, ABCB7 in Proben von Human zu detektieren.

Kurzübersicht für ABCB7 Antikörper (ABIN7468006)

Target: ABCB7 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 (ABCB7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABCB7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ABCB7 Antikörper

Kreuzreaktivität: Human, Maus

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human ABCB7. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.2 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu ABCB7

Target: ABCB7 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 (ABCB7))

Andere Bezeichnung: ATP binding cassette subfamily B member 7

Hintergrund:

Synonyms: ATP binding cassette subfamily B member 7 , ABC7 , ASAT , Atm1p , EST140535

Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia. [provided by RefSeq]

Molekulargewicht: 83 kDa

Gen-ID: 22

UniProt: O75027

Pathways: Transition Metal Ion Homeostasis