GIPR Antikörper (N-Term)

Produktnummer ABIN7467374

Dieses Anti-GIPR-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GIPR in WB. Geeignet für Human.

Kurzübersicht für GIPR Antikörper (N-Term) (ABIN7467374)

Target: GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GIPR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GIPR Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Ratte

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human GIPR. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: rat brain

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.53 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu GIPR

Target: GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))

Andere Bezeichnung: gastric inhibitory polypeptide receptor

Hintergrund: Gastric inhibitory polypeptide receptor , PGQTL2,Gastric inhibitory polypeptide (GIP, MIM 137240), also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid polypeptide synthesized by K cells of the duodenum and small intestine. It was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release potently in the presence of elevated glucose. The insulinotropic effect on pancreatic islet beta-cells was then recognized to be the principal physiologic action of GIP. Together with glucagon-like peptide-1, GIP is largely responsible for the secretion of insulin after eating. It is involved in several other facets of the anabolic response.[supplied by OMIM]

Molekulargewicht: 53 kDa

Gen-ID: 2696

UniProt: P48546

Pathways: Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling