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PNP Antikörper

Der Kaninchen Polyklonal Anti-PNP-Antikörper wurde für WB, IHC, ICC und IF validiert. Er ist geeignet, PNP in Proben von Human zu detektieren.
Produktnummer ABIN7467304

Kurzübersicht für PNP Antikörper (ABIN7467304)

Target

Alle PNP Antikörper anzeigen
PNP (Purine Nucleoside Phosphorylase (PNP))

Reaktivität

  • 34
  • 8
  • 7
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 36
  • 6
  • 1
  • 1
Kaninchen

Klonalität

  • 39
  • 5
Polyklonal

Konjugat

  • 32
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser PNP Antikörper ist unkonjugiert

Applikation

  • 32
  • 18
  • 18
  • 15
  • 10
  • 9
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
  • Kreuzreaktivität

    Human

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human Purine nucleoside phosphorylase. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Positive Control: Raji

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    PNP (Purine Nucleoside Phosphorylase (PNP))

    Andere Bezeichnung

    purine nucleoside phosphorylase

    Substanzklasse

    Viral Protein

    Hintergrund

    Purine nucleoside phosphorylase , NP , PRO1837 , PUNP,This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2. [provided by RefSeq]

    Molekulargewicht

    32 kDa

    Gen-ID

    4860

    UniProt

    P00491

    Pathways

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus
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