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FBXO8 Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FBXO8 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7466373

Kurzübersicht für FBXO8 Antikörper (ABIN7466373)

Target

Alle FBXO8 Antikörper anzeigen
FBXO8 (F-Box Protein 8 (FBXO8))

Reaktivität

  • 16
  • 12
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 13
  • 9
Kaninchen

Klonalität

  • 14
  • 8
Polyklonal

Konjugat

  • 17
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser FBXO8 Antikörper ist unkonjugiert

Applikation

  • 21
  • 13
  • 3
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Kreuzreaktivität

    Human, Maus

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human FBXO8. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Positive Control: JC , Raji

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    FBXO8 (F-Box Protein 8 (FBXO8))

    Andere Bezeichnung

    F-box protein 8

    Hintergrund

    F-box protein 8 , DC10 , FBS , FBX8,This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity. [provided by RefSeq]

    Molekulargewicht

    37 kDa

    Gen-ID

    26269

    UniProt

    Q9NRD0
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