Coagulation Factor X Antikörper

Produktnummer ABIN7466218

Der Maus Monoklonal Anti-Coagulation Factor X-Antikörper wurde für WB, ICC und IF validiert. Er ist geeignet, Coagulation Factor X in Proben von Human zu detektieren.

Kurzübersicht für Coagulation Factor X Antikörper (ABIN7466218)

Target: Coagulation Factor X (F10)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Coagulation Factor X Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Klon: GT268

Produktdetails anti-Coagulation Factor X Antikörper

Kreuzreaktivität: Human

Aufreinigung: Affinity purified by Protein G.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Factor X. The exact sequence is proprietary.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: human F10-transfected 293T cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, No Preservative

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu Coagulation Factor X

Target: Coagulation Factor X (F10)

Andere Bezeichnung: coagulation factor X

Hintergrund: Coagulation factor X , FX , FXA,This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds, the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. [provided by RefSeq]

Molekulargewicht: 55 kDa

Gen-ID: 2159

UniProt: P00742