GRAF Antikörper (C-Term)

Produktnummer ABIN7466095

Der Kaninchen Polyklonal Anti-GRAF-Antikörper wurde für WB validiert. Er ist geeignet, GRAF in Proben von Human zu detektieren.

Kurzübersicht für GRAF Antikörper (C-Term) (ABIN7466095)

Target: GRAF (ARHGAP26) (rho GTPase Activating Protein 26 (ARHGAP26))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRAF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GRAF Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human GRAF. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: HepG2

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu GRAF

Target: GRAF (ARHGAP26) (rho GTPase Activating Protein 26 (ARHGAP26))

Andere Bezeichnung: Rho GTPase activating protein 26

Hintergrund: Rho GTPase activating protein 26 , GRAF , GRAF1 , OPHN1L , OPHN1L1,Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Molekulargewicht: 92 kDa

Gen-ID: 23092

UniProt: Q9UNA1