CAPN10 Antikörper
Kurzübersicht für CAPN10 Antikörper (ABIN7465837)
Target
Alle CAPN10 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Kreuzreaktivität
- Human
-
Aufreinigung
- Purified by antigen-affinity chromatography.
-
Immunogen
- Recombinant protein encompassing a sequence within the center region of human Calpain 10. The exact sequence is proprietary.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
Kommentare
-
Positive Control: HeLa
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 0.48 mg/mL
-
Buffer
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
-
Konservierungsmittel
- Thimerosal (Merthiolate)
-
Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- CAPN10 (Calpain 10 (CAPN10))
-
Andere Bezeichnung
- calpain 10
-
Hintergrund
- Calpain 10 , CANP10 , NIDDM1,Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation, domain II, the protease domain, domain III, a linker domain of unknown function, and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM) and located within the NIDDM1 region. Multiple alternative transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
-
Molekulargewicht
- 75 kDa
-
Gen-ID
- 11132
-
UniProt
- Q9HC96
-
Pathways
- Positive Regulation of Peptide Hormone Secretion
Target
-