CELF1 Antikörper

Produktnummer ABIN7465510

Der Kaninchen Polyklonal Anti-CELF1-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, CELF1 in Proben von Human zu detektieren.

Kurzübersicht für CELF1 Antikörper (ABIN7465510)

Target: CELF1 (CUGBP, Elav-Like Family Member 1 (CELF1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CELF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CELF1 Antikörper

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human CUGBP1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: A549

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.24 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu CELF1

Target: CELF1 (CUGBP, Elav-Like Family Member 1 (CELF1))

Andere Bezeichnung: CUGBP Elav-like family member 1

Hintergrund: CUGBP Elav-like family member 1 , BRUNOL2 , CUG-BP , CUGBP , CUGBP1 , EDEN-BP , NAB50 , NAPOR , hNab50,Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

Molekulargewicht: 52 kDa

Gen-ID: 10658

UniProt: Q92879

Pathways: Ribonucleoprotein Complex Subunit Organization