NOB1 Antikörper

Produktnummer ABIN7465472

Dieses Anti-NOB1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NOB1 in WB. Geeignet für Human.

Kurzübersicht für NOB1 Antikörper (ABIN7465472)

Target: NOB1 (RNA-Binding Protein NOB1 (NOB1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NOB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NOB1 Antikörper

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human NOB1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: A431 , Jurkat

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.01 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu NOB1

Target: NOB1 (RNA-Binding Protein NOB1 (NOB1))

Andere Bezeichnung: NIN1 (RPN12) binding protein 1 homolog

Hintergrund: NIN1 (RPN12) binding protein 1 homolog , ART-4 , MST158 , MSTP158 , NOB1P , PSMD8BP1,In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 [PubMed 19706509]).[supplied by OMIM]

Molekulargewicht: 47 kDa

Gen-ID: 28987

UniProt: Q9ULX3

Pathways: Protein targeting to Nucleus