EIF3H Antikörper
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- Target Alle EIF3H Antikörper anzeigen
- EIF3H (Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser EIF3H Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Human
- Aufreinigung
- Affinity purified by Protein G.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human eIF3H / EIF3S3. The exact sequence is proprietary.
- Klon
- GT2712
- Isotyp
- IgG1
- Top Product
- Discover our top product EIF3H Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Kommentare
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Positive Control: A431
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS, No Preservative
- Konservierungsmittel
- Without preservative
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- EIF3H (Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H))
- Andere Bezeichnung
- eukaryotic translation initiation factor 3 subunit H (EIF3H Produkte)
- Synonyme
- EIF3S3 antikoerper, eIF3-gamma antikoerper, eIF3-p40 antikoerper, 1110008A16Rik antikoerper, 40kD antikoerper, 9430017H16Rik antikoerper, EIF3-P40 antikoerper, EIF3-gamma antikoerper, Eif3s3 antikoerper, eif3s3 antikoerper, eIF-3p40 antikoerper, En10 antikoerper, AO090038000435 antikoerper, EIF3H antikoerper, eIF3h antikoerper, BcDNA:GM14618 antikoerper, CG9124 antikoerper, Dmel\\CG9124 antikoerper, eIF-3 antikoerper, eIF3-S3 antikoerper, eIf3-p44 antikoerper, l(2)k09003 antikoerper, eIF3h-A antikoerper, eif3h antikoerper, fj02c04 antikoerper, wu:fj02c04 antikoerper, zgc:101085 antikoerper, eIF3h-B antikoerper, zgc:123049 antikoerper, eukaryotic translation initiation factor 3 subunit H antikoerper, eukaryotic translation initiation factor 3, subunit H antikoerper, eukaryotic translation initiation factor 3 subunit H S homeolog antikoerper, eukaryotic translation initiation factor 3 subunit H-like antikoerper, Eukaryotic initiation factor 3 p40 subunit antikoerper, eukaryotic translation initiation factor 3, subunit H, a antikoerper, Eukaryotic translation initiation factor 3 subunit H antikoerper, translation initiation factor eIF3h (p40) antikoerper, eukaryotic translation initiation factor 3, subunit H, b antikoerper, EIF3H antikoerper, Eif3h antikoerper, eif3h antikoerper, eif3h.S antikoerper, eIF3h antikoerper, AOR_1_722074 antikoerper, PAAG_02837 antikoerper, VDBG_01433 antikoerper, MGYG_06658 antikoerper, LOC100196680 antikoerper, eIF-3p40 antikoerper, eif3ha antikoerper, eif-3.H antikoerper, SPAC821.05 antikoerper, eif3hb antikoerper
- Hintergrund
- Eukaryotic translation initiation factor 3 subunit H , EIF3S3 , eIF3-gamma , eIF3-p40,Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).
- Molekulargewicht
- 40 kDa
- Gen-ID
- 8667
- UniProt
- O15372
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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