MIP Antikörper (PE)

Produktnummer ABIN719586

Dieses Anti-MIP-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MIP in IF (p). Geeignet für Human, Maus, Ratte, Meerschweinchen, Schwein, Huhn und Rind (Kuh).

Kurzübersicht für MIP Antikörper (PE) (ABIN719586)

Target: MIP (Major Intrinsic Protein of Lens Fiber (MIP))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Schwein, Huhn, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MIP Antikörper ist konjugiert mit PE

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-MIP Antikörper (PE)

Spezifität: Excitation / Emission Wavelengths: 565nm/578nm

Kreuzreaktivität: Ratte (Rattus), Huhn, Schwein, Rind (Kuh), Meerschweinchen

Aufreinigung: purified by Protein A

Immunogen: KLH conjugated synthetic peptide derived from human AQP0

Isotyp: IgG

Anwendungsinformationen

Kommentare:

Excitation / Emission wavelength: 496nm / 578nm

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 µg/µL

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4 °C for 12 months

Haltbarkeit: 12 months

Details zu MIP

Target: MIP (Major Intrinsic Protein of Lens Fiber (MIP))

Andere Bezeichnung: AQP0

Hintergrund: Water is a critical component of all living cells. Interestingly, tissue membranes show a great degree of water permeability. Mammalian red cells, renal proximal tubules, and descending thin limb of Henle are extraordinarily permeable to water. Water crosses hydrophobic plasma membranes either by simple diffusion or through a facilitative transport mechanism mediated by special protein aquaporins. Aquaporin 0 or MIP26 (major intrinsic protein 26kD), and Aquaporin 1 has been the foundation of the growing family of aquaporins. The lens specific Aquaporin 0 represents up to 80% of total lens membrane protein. Defects in Aquaporin 0 are a cause of autosomal recessive congenital cataract. The lens opacity mutation (LOP) is an AA substitution that inhibits targeting of MIP to the cell membrane. Human Aquaporin 0 is a 263 amino acid transmembrane protein belonging to the MIP family. Aquaporin families of proteins are predicted to contain six transmembrane domains. The N and C terminus are predicted to be cytoplasmic.

Molekulargewicht: 28kDa

Gen-ID: 4284