PC Antikörper (C-Term)

Produktnummer ABIN7465195

Produktdetails anti-PC Antikörper

Target: PC (Pyruvate Carboxylase (PC))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF), RNA-Binding Protein Immunoprecipitation (RIP)

Kreuzreaktivität: Human, Ratte

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human Pyruvate Carboxylase. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:857. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: 293T , A431 , HeLa , HepG2

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.69 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu PC

Target: PC (Pyruvate Carboxylase (PC))

Andere Bezeichnung: pyruvate carboxylase (PC Produkte)

Synonyme: BcDNA antikoerper, BcDNA:GH06348 antikoerper, Dmel\\CG1516 antikoerper, PC antikoerper, pyc antikoerper, wu:fb82g08 antikoerper, wu:fj85g01 antikoerper, PCX antikoerper, BA4157 antikoerper, Pc antikoerper, Pcb antikoerper, PCB antikoerper, Pcx antikoerper, Pyruvate carboxylase antikoerper, pyruvate carboxylase b antikoerper, PYruvate Carboxylase antikoerper, pyruvate carboxylase antikoerper, pyruvate carboxylase Pyr1 antikoerper, PCB antikoerper, pcxb antikoerper, pyc-1 antikoerper, PC antikoerper, pyc antikoerper, pyr1 antikoerper, CNF00650 antikoerper, PYC1 antikoerper, Ndas_1152 antikoerper, Ilyop_2503 antikoerper, Calni_0495 antikoerper, Ftrac_1004 antikoerper, Plabr_3574 antikoerper, Sgly_2936 antikoerper, Celly_0558 antikoerper, Hipma_0131 antikoerper, Halhy_1567 antikoerper, Mesop_1269 antikoerper, Pcx antikoerper, Pc antikoerper

Hintergrund: Pyruvate carboxylase , PCB,This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq]

Molekulargewicht: 130 kDa

Gen-ID: 5091

UniProt: P11498