PHF2 Antikörper

Produktnummer ABIN7465155

Produktdetails anti-PHF2 Antikörper

Target: PHF2 (PHD Finger Protein 2 (PHF2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PHF2. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: 293T , A431 , HeLa , HepG2

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu PHF2

Target: PHF2 (PHD Finger Protein 2 (PHF2))

Andere Bezeichnung: PHD finger protein 2 (PHF2 Produkte)

Synonyme: CENP-35 antikoerper, GRC5 antikoerper, JHDM1E antikoerper, im:4200679 antikoerper, phf8 antikoerper, wu:fa14c10 antikoerper, PHD finger protein 2 antikoerper, PHF2 antikoerper, Phf2 antikoerper, phf2 antikoerper

Hintergrund: PHD finger protein 2 , CENP-35 , GRC5 , JHDM1E , KDM7C,Probable regulator of histone methyltransferase complexes. Recruited to trimethylated 'Lys-4' of histone H3 (H3K4me3) at rDNA promoters and promotes expression of rDNA. Was reported to have histone demethylase activity by itself and specifically demethylate monomethylated 'Lys-9' of histone H3 (H3K9me1), an epigenetic repressive mark. However, this activity is unclear in vivo and requires additional evidence.

Molekulargewicht: 121 kDa

Gen-ID: 5253

UniProt: O75151