Emerin Antikörper (AA 25-125) (Cy3)

Produktnummer ABIN719564

Produktdetails anti-Emerin Antikörper (Cy3)

Target: Emerin (EMD)

Bindungsspezifität: AA 25-125

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Emerin Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Emerin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Emerin

Target: Emerin (EMD)

Andere Bezeichnung: Emerin (EMD Produkte)

Synonyme: fj58f01 antikoerper, wu:fj58f01 antikoerper, EMD antikoerper, Bocks antikoerper, Bocksbeutel antikoerper, CG9424 antikoerper, Dmel\\CG9424 antikoerper, emerin antikoerper, emd antikoerper, xemd1 antikoerper, xemerin2 antikoerper, xemd2 antikoerper, xemerin1 antikoerper, EDMD antikoerper, LEMD5 antikoerper, STA antikoerper, AW550900 antikoerper, Sta antikoerper, emerin antikoerper, emerin (Emery-Dreifuss muscular dystrophy) antikoerper, bocksbeutel antikoerper, emerin L homeolog antikoerper, emerin S homeolog antikoerper, EMD antikoerper, emd antikoerper, bocks antikoerper, emd.L antikoerper, emd.S antikoerper, Emd antikoerper

Hintergrund:

Synonyms: EDMD, EMD, EMD_HUMAN, Emerin, Emery Dreuss muscular dystrophy, STA.

Background: Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. Required for proper localization of non-farnesylated prelamin-A/C.Tissue specificity, Skeletal muscle, heart, colon, testis, ovary and pancreas.

Gen-ID: 2010