STEAP3 Antikörper

Produktnummer ABIN7464576

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch STEAP3 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für STEAP3 Antikörper (ABIN7464576)

Target: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STEAP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-STEAP3 Antikörper

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human STEAP3. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: HepG2 cytoplasm extract

Validation: Orthogonal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.79 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu STEAP3

Target: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Andere Bezeichnung: STEAP3 metalloreductase

Hintergrund: STEAP3 metalloreductase , AHMIO2 , STMP3 , TSAP6 , dudlin-2 , dudulin-2 , pH yde,Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NAD(+) as acceptor (By similarity). May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.

Molekulargewicht: 55 kDa

Gen-ID: 55240

UniProt: Q658P3

Pathways: Transition Metal Ion Homeostasis