WIPI1 Antikörper (C-Term)

Produktnummer ABIN7464565

Der Kaninchen Polyklonal Anti-WIPI1-Antikörper wurde für WB validiert. Er ist geeignet, WIPI1 in Proben von Human zu detektieren.

Kurzübersicht für WIPI1 Antikörper (C-Term) (ABIN7464565)

Target: WIPI1 (WD Repeat Domain, phosphoinositide Interacting 1 (WIPI1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WIPI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-WIPI1 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human WIPI1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:20000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: HepG2 , human WIPI1-transfected 293T cells

Validation: Overexpression

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu WIPI1

Target: WIPI1 (WD Repeat Domain, phosphoinositide Interacting 1 (WIPI1))

Andere Bezeichnung: WD repeat domain, phosphoinositide interacting 1

Hintergrund: WD repeat domain, phosphoinositide interacting 1 , ATG18 , ATG18A , WIPI49,WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI1, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).[supplied by OMIM]

Molekulargewicht: 49 kDa

Gen-ID: 55062

UniProt: Q5MNZ9

Pathways: Nuclear Hormone Receptor Binding, ER-Nucleus Signaling