GLUL Antikörper

Produktnummer ABIN7464227

Dieses Anti-GLUL-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GLUL in WB, IHC, IF, IHC (p), ICC, IP, IHC (fro) und IHC (wm). Geeignet für Human.

Kurzübersicht für GLUL Antikörper (ABIN7464227)

Target: GLUL (Glutamate-Ammonia Ligase (GLUL))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLUL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Whole Mount) (IHC (wm))

Güteklasse: KO Validated

Produktdetails anti-GLUL Antikörper

Kreuzreaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio)

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Full length human Glutamine synthetase Recombinant protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: 293T , DDDDK-tagged GLUL-transfected 293T

Validation: KO/KD, Orthogonal, Overexpression

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu GLUL

Target: GLUL (Glutamate-Ammonia Ligase (GLUL))

Andere Bezeichnung: glutamate-ammonia ligase

Hintergrund: Glutamate-ammonia ligase , GLNS , GS , PIG43 , PIG59,Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling (Haberle et al., 2005 [PubMed 16267323]). Fetal glutamine requirements are very high and depend largely on active glutamine synthesis and the release of glutamine into the fetal circulation by the placenta. Glutamine synthetase (EC 6.3.1.2), also called glutamate-ammonia ligase (GLUL), is expressed throughout the body and plays an important role in controlling body pH and in removing ammonia from the circulation. The enzyme clears L-glutamate, the major neurotransmitter in the central nervous system, from neuronal synapses (see references in Clancy et al., 1996 [PubMed 8975719]).[supplied by OMIM]

Molekulargewicht: 42 kDa

Gen-ID: 2752

UniProt: P15104

Pathways: Positive Regulation of Peptide Hormone Secretion