DGCR8 Antikörper (N-Term)

Produktnummer ABIN7464181

Der Kaninchen Polyklonal Anti-DGCR8-Antikörper wurde für WB und IP validiert. Er ist geeignet, DGCR8 in Proben von Human zu detektieren.

Kurzübersicht für DGCR8 Antikörper (N-Term) (ABIN7464181)

Target: DGCR8 (DiGeorge Syndrome Critical Region Gene 8 (DGCR8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DGCR8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Güteklasse: KO Validated

Produktdetails anti-DGCR8 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Frosch, Human

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human DGCR8. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: 293T , A431 , HeLa , HepG2

Validation: KO/KD

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.15 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu DGCR8

Target: DGCR8 (DiGeorge Syndrome Critical Region Gene 8 (DGCR8))

Andere Bezeichnung: DGCR8 microprocessor complex subunit

Hintergrund: DGCR8 microprocessor complex subunit , C22orf12 , DGCRK6 , Gy1 , pasha,This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq]

Molekulargewicht: 86 kDa

Gen-ID: 54487

UniProt: Q8WYQ5

Pathways: Regulatorische RNA Pathways