RNPS1 Antikörper (N-Term)

Produktnummer ABIN7464180

Produktdetails anti-RNPS1 Antikörper

Target: RNPS1 (RNA-Binding Protein S1 (RNPS1))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNPS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human, Maus

Aufreinigung: Purified by antigen-affinity chromatography.

Güteklasse: KO Validated

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human RNPS1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: 293T , A431 , HeLa , HepG2

Validation: KO/KD

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu RNPS1

Target: RNPS1 (RNA-Binding Protein S1 (RNPS1))

Andere Bezeichnung: RNA binding protein with serine rich domain 1 (RNPS1 Produkte)

Synonyme: E5.1 antikoerper, ribonucleic acid binding protein S1 antikoerper, RNA binding protein with serine rich domain 1 antikoerper, RNA binding protein S1, serine-rich domain antikoerper, Rnps1 antikoerper, RNPS1 antikoerper

Hintergrund: RNA binding protein with serine rich domain 1 , E5.1,This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Two splice variants have been found for this gene, both variants encode the same protein. [provided by RefSeq]

Molekulargewicht: 34 kDa

Gen-ID: 10921

UniProt: Q15287